2026-04-18 08:53:33Sortilin介导的MedTAC：mRNA编码溶酶体靶向嵌合体实现膜蛋白快速持久降解
Sortilin介导的MedTAC：mRNA编码溶酶体靶向嵌合体实现膜蛋白快速持久降解[基础信息]文献信息卡片：[题目]Sortilin-MediatedRapid,PreciseandSustainedDegradationofMembranePr...
了解详情Sortilin介导的MedTAC：mRNA编码溶酶体靶向嵌合体实现膜蛋白快速持久降解[基础信息]文献信息卡片：[题目]Sortilin-MediatedRapid,PreciseandSustainedDegradationofMembranePr...
了解详情KineTAC：模块化细胞因子受体靶向嵌合体拓展胞外蛋白降解的组织特异性边界[题目]Modularcytokinereceptor-targetingchimerasfortargeteddegradationofcellsurfaceandextr...
了解详情细胞外靶向蛋白降解(eTPD)：技术全景梳理与临床转化路径前瞻[题目]Extracellulartargetedproteindegradation:anemergingmodalityfordrugdiscovery[期刊]NatureReview...
了解详情工程化病毒样纳米颗粒（VNP）实现多模式蛋白降解，助力增强肿瘤治疗·【题目】EngineeredVirus-LikeNanoparticlesEnableMultimodalProteinDegradationforEnhancedTumorTher...
了解详情表观遗传蛋白降解联合光动力治疗：BRD4-PROTAC阻断CCL5耐药通路增强抗肿瘤效应[题目]EmployingepigeneticproteindegradationtechniquestoblockCCL5-mediatedphotodynam...
了解详情全基因组CRISPR筛选揭示LYTAC膜蛋白降解的细胞决定因素[题目]Elucidatingthecellulardeterminantsoftargetedmembraneproteindegradationbylysosome-targeting...
了解详情[题目]DirectedevolutionofgeneticallyencodedLYTACsforcell-mediateddelivery[期刊]PNAS(ProceedingsoftheNationalAcademyofSciences)[影响...
了解详情[题目]Developmentoffolatereceptortargetingchimerasforcancerselectivedegradationofextracellularproteins[期刊]NatureCommunications[...
了解详情EndoTag：从头设计胞吞诱导蛋白实现膜蛋白降解与下游信号放化的双功能调控【题目】Designedendocytosis-inducingproteinsdegradetargetsandamplifysignals【期刊】Nature【影响因子】...
了解详情【题目】Designofamucin-selectiveproteasefortargeteddegradationofcancer-associatedmucins【期刊】NatureBiotechnology【影响因子】33.1【DOI】10.1...
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